Decoding Cell Signaling: Struggle and Serendipity
Recent research is zeroing in on mTOR as a useful target for therapies for Glioma and other cancers.
Other recent research points to mTOR as a key to treating obesity.
mTor is key to the initiation of protein synthesis, and the initiation of cell cycling and division. The process of muscular hypertrophy utilises mTOR, both in skeletal muscle and smooth muscle. This places mTOR at the center of possible treatments for vascular stenosis due to smooth muscle hypertrophy.
It is the sheer complexity of the cell signaling pathways that causes potentially revolutionary research to proceed at a snail's pace. It is important that the therapeutic agent target only those molecules that achieve a useful result. Achieving the proper level of specificity involves both struggle and serendipity.
Labels: cell signalling