A1 "Sauce": A Fertile Aphrodisiac

Androstadienone (A1) is a musky steroid that elevates the mood of women, increases feelings of "caring", and makes a woman more comfortable and ready for intimacy.

“It has been shown that when women ovulate, their response to androstadienone is strongest,” says Andreas Keller, a postdoc in Leslie Vosshall’s Laboratory of Neurogenetics and Behavior. “It is also a time when women are apt to reproduce.” By exposing ovulating women to androstadienone and measuring their physiological responses to it, Keller and Vosshall ultimately hope to figure out whether androstadienone, also a derivative of testosterone and potential social signal, affects how men and women interact with one another.___Rockefeller University Hospital

The Rockefeller study intends to enlarge upon the scientific knowledge of the effect of A1 on women--specifically women who are ovulating, thus most fertile. Scientists have begun mapping the areas of the human cortex that are activated by A1. It has also been discovered that not just any "musk" will do. A1 appears to act on the female brain in a way that is unique among "musks."

Previously, we have shown that Δ4,16-androstadien-3-one modulates psychological state, reducing negative mood and increasing positive mood (Jacob and McClintock, 2000; Jacob et al., 2001a). In order to determine whether similar musky compounds also produce these effects, we compared the effects of androstadienone to those of androstenol and muscone, measuring the psychological states of 37 participants. Androstenol and muscone were chosen because they too have a musky odor at high concentrations, while androstenol is a steroid like androstadienone and muscone is not....Androstadienone's effects on psychological state were unique in comparison with those of androstenol and with muscone. Exposure through passive inhalation, rather than dermal contact, was sufficient for these effects.____Source

A1 is available in 10 ml bottles here for US $79.95

Animals are attracted to each other through pheromonal signaling. Apparently, so are humans. The observed "addictive" nature of falling in love goes deeper than the psychological and physical fulfilling of the needs for pleasure and companionship. The brain itself is altered, and shifted into a state of heightened receptivity, by chemical signaling independent of visual, tactile, or verbal exchanges.

The consummate seducer or seductress learns to create a "gestalt", a holistic multi-sensory experience that "opens the gates and lowers the drawbridge" to the fullest extent possible. It is an art that can be learned, but until recently we had all been largely limited to what nature had given us.

A1 is just another in a long line of prosthetic and augmentative love aids which are increasingly being utilised in the ages-long battle of sex.

In the 1970s, Preti said, a researcher named Martha McClintock discovered the menstrual cycles of women who live together synchronize because of unconscious odor cues. Likewise, Preti, an organic chemist by training, said studies have found chemicals in underarm secretions affect neuroendocrine levels, which alter mood.

He and colleague Charles Wysocki discovered that the levels of luteinizing hormone, which affects the timing of ovulation and the length of menstrual cycles, increased in women after sniffing men's underarm secretions.

...Scientists have been able to conclude that pheromones do play a role in altering behaviors in animals and insects. Animals release pheromones to mark their territory, to alert others of danger, or to mark the trail used to find food.____Source

But it also appears that humans are animals after all--despite the denials--human brains are strongly affected by specific olfactory triggers.