... to fully realize the brain’s potential to teach us how to make machines learn and think, further advances are needed in the technology for understanding the brain in the first place. Modern noninvasive methods for simultaneously measuring the activity of many brain cells have provided a major boost in that direction, but details of the brain’s secret communication code remain to be deciphered. Nerve cells communicate by firing electrical pulses that release small molecules called neurotransmitters, chemical messengers that hop from one nerve cell to a neighbor, inducing the neighbor to fire a signal of its own (or, in some cases, inhibiting the neighbor from sending signals). Because each nerve cell receives messages from tens of thousands of others, and circuits of nerve cells link up in complex networks, it is extremely difficult to completely trace the signaling pathways.
Furthermore, the code itself is complex — nerve cells fire at different rates, depending on the sum of incoming messages. Sometimes the signaling is generated in rapid-fire bursts; sometimes it is more leisurely. And much of mental function seems based on the firing of multiple nerve cells around the brain in synchrony. _GrandEngineeringChallenge
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