17 November 2009

Aphrodisiac for Successful, Satisfying Sex


Flibanserin was once an antidepressant, but not a very good one. Some women on flibanserin did notice that even though their depression did not get much better, their sex lives did. Now, a pooled set of four clinical trials of flibanserin show a significant aphrodisiac response in women -- particularly at the dose of 100 mg at bedtime.
These trials were the first ever to test a therapy that works at the level of the brain to enhance libido in women reporting low sexual desire, said John M. Thorp Jr., M.D., McAllister distinguished professor of obstetrics and gynecology at the University of North Carolina at Chapel Hill School of Medicine and the principal investigator for North America in the studies.

"Flibanserin was a poor antidepressant," Thorp said. "However, astute observers noted that it increased libido in laboratory animals and human subjects. So, we conducted multiple clinical trials and the women in our studies who took it for hypoactive sexual desire disorder reported significant improvements in sexual desire and satisfactory sexual experiences.

...Studies have shown that the prevalence of hypoactive sexual desire disorder in the U.S. ranges from 9 percent to 26 percent of women, depending on age and menopausal status. Flibanserin is currently an investigational drug and is available only to women taking part in clinical trials.

...The researchers concluded that treatment with 100 milligrams of flibanserin once a day was associated with significant improvements versus placebo in the number of satisfying sexual events (SSE) reported, sexual desire (as measured by eDiary and FSFI desire domain), a reduction in distress associated with sexual dysfunction (as measured by FSDS-R and its Item 13), and sexual functioning as measured by FSFI. _SD
The science of sexual gratification and fulfillment has been largely neglected over the past centuries of rapid scientific discovery. But that is about to change. Modern PC prudishness is scheduled to be washed away in a deluge of evolutionary consciousness.

Besides -- what good is long life, prosperity, and high intelligence, if your life holds no satisfaction or pleasure? Humans are emotional and physical animals, and they require emotional and physical gratification for optimal development and happiness.

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